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GENE INFORMATION ? »
Gene information from Ensembl and Entrez, as well as links to available gene identifiers are displayed here. Information was retrieved from Ensembl if not indicated otherwise.
Gene name	SSB (HGNC Symbol)
Synonyms	La, La/SSB, LARP3
Description	Sjogren syndrome antigen B (autoantigen La) (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is involved in diverse aspects of RNA metabolism, including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion, processing 5' and 3' ends of pre-tRNA precursors, acting as an RNA chaperone, and binding viral RNAs associated with hepatitis C virus. Autoantibodies reacting with this protein are found in the sera of patients with Sjogren syndrome and systemic lupus erythematosus. Alternative promoter usage results in two different transcript variants which encode the same protein. [provided by RefSeq, Jun 2014]
Chromosome	2
Cytoband	q31.1
Chromosome location (bp)	169791933 - 169812064
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000138385 (version 78.38)
Entrez gene	6741
UniProt	P05455 (UniProt - Evidence at protein level)
neXtProt	NX_P05455
Antibodypedia	SSB antibodies