![]() ![]() GENE INFORMATION ? » | |
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Gene name | PCNA |
Synonyms | |
Description | Proliferating cell nuclear antigen (HGNC Symbol) |
Entrez gene summary | The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008] |
Chromosome | 20 |
Cytoband | p12.3 |
Chromosome location (bp) | 5114953 - 5126626 |
Protein evidence | Evidence at protein level (all genes) |
ENSG00000132646 (version 78.38) | |
5111 | |
P12004 (UniProt - Evidence at protein level) | |
NX_P12004 | |
PCNA antibodies | |
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