FibroAtlas is a manually curated gene-centric knowledgebase for human fibrosis. Fibrosis is a highly dynamic biological process caused by prolonged injury, and FibroAtlas is helpful for better understanding of complex birosis process, novel biomarker and also treatment responses. The current version of FibroAtlas contains 1,439 well-annotated genes.
1. Wynn TA. (2008) Cellular and molecular mechanisms of fibrosis. Journal of Pathology, 214(2), 199–210.
2. Wynn TA. (2004) Fibrotic disease and the T(H)1/T(H)2 paradigm. Nature Reviews Immunology 4(8),583-594.
3. Max A. Seibold, et al. (2011) A Common MUC5B Promoter Polymorphism and Pulmonary Fibrosis. New England Journal of Medicine,364(16),1503-1512.
4. van Bon L, Affand AJ, Broen, J, et al. (2014) Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosis. New England Journal of Medicine, 370(5), 433-443.
Number of Fibrosis-related Genes : 1439
Number of Diseases : 16
Number of Biomarkers : 85