CCR6
| GENE INFORMATIONi | |
|---|---|
| Gene name | CCR6 (HGNC Symbol) |
| Synonyms | BN-1, CD196, CKR-L3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, STRL22 |
| Description | C-C motif chemokine receptor 6 (HGNC Symbol) |
| Entrez gene summary | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
| Chromosome | 6 |
| Cytoband | q27 |
| Chromosome location (bp) | 167111807 - 167139696 |
| Protein evidence | Evidence at protein level (all genes) |
| Ensembl | ENSG00000112486 (version 88.38) |
| Entrez gene | 1235 |
| UniProt | P51684 (UniProt - Evidence at protein level) |
| neXtProt | NX_P51684 |
| Antibodypedia | CCR6 antibodies |