CCL21
| GENE INFORMATIONi | |
|---|---|
| Gene name | CCL21 (HGNC Symbol) |
| Synonyms | 6Ckine, CKb9, ECL, exodus-2, SCYA21, SLC, TCA4 |
| Description | C-C motif chemokine ligand 21 (HGNC Symbol) |
| Entrez gene summary | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014] |
| Chromosome | 9 |
| Cytoband | p13.3 |
| Chromosome location (bp) | 34709005 - 34710124 |
| Protein evidence | Evidence at protein level (all genes) |
| Ensembl | ENSG00000137077 (version 88.38) |
| Entrez gene | 6366 |
| UniProt | O00585 (UniProt - Evidence at protein level) |
| neXtProt | NX_O00585 |
| Antibodypedia | CCL21 antibodies |