GENE INFORMATIONi | |
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Gene name | CCL17 (HGNC Symbol) |
Synonyms | ABCD-2, SCYA17, TARC |
Description | C-C motif chemokine ligand 17 (HGNC Symbol) |
Entrez gene summary | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014] |
Chromosome | 16 |
Cytoband | q21 |
Chromosome location (bp) | 57404767 - 57416062 |
Protein evidence | Evidence at protein level (all genes) |
Ensembl | ENSG00000102970 (version 88.38) |
Entrez gene | 6361 |
UniProt | Q92583 (UniProt - Evidence at protein level) |
neXtProt | NX_Q92583 |
Antibodypedia | CCL17 antibodies |