GENE INFORMATIONi | |
---|---|
Gene name | BECN1 (HGNC Symbol) |
Synonyms | ATG6, VPS30 |
Description | Beclin 1 (HGNC Symbol) |
Entrez gene summary | This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
Chromosome | 17 |
Cytoband | q21.31 |
Chromosome location (bp) | 42810134 - 42833350 |
Protein evidence | Evidence at protein level (all genes) |
Ensembl | ENSG00000126581 (version 88.38) |
Entrez gene | 8678 |
UniProt | Q14457 (UniProt - Evidence at protein level) |
neXtProt | NX_Q14457 |
Antibodypedia | BECN1 antibodies |