BECN1

GENE INFORMATIONi
Gene nameBECN1 (HGNC Symbol)
SynonymsATG6, VPS30
DescriptionBeclin 1 (HGNC Symbol)
Entrez gene summaryThis gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Chromosome17
Cytobandq21.31
Chromosome location (bp)42810134 - 42833350
Protein evidenceEvidence at protein level (all genes)
EnsemblENSG00000126581 (version 88.38)
Entrez gene8678
UniProtQ14457 (UniProt - Evidence at protein level)
neXtProtNX_Q14457
AntibodypediaBECN1 antibodies