Notice (08/04/2020):
Owing to the domain name change of our research center, AllerGAtlas will be moved to new url: Please simultaneously try both urls. Sorry for the inconvenience!

E.g. CCL22
E.g. Atopic dermatitis
Search by Protein Sequence(example)
Search by Nucleotide Sequence(example)

   AllerGAtlas is a manually curated database for human allergy-related genes.Allergy is a detrimental hypersensitive response to innocuous environmental antigen ,which is caused by the effect of interaction between environmental factors and multiple genetic predisposition. Hundreds of allergy-related genes have been identified to illustrate the epidemiology and pathogenesis of allergic diseases,which are associated with better endophenotype, novel biomarkers,early-life risk factors and individual differences in treatment responses. Here we present a database containing 1,195 well-annotated human allergy-related genes, determined by text-mining and manual curation.

1. Ober, Carole, and Tsung‐Chieh Yao. The genetics of asthma and allergic disease: a 21st century perspective. Immunological reviews 242.1 (2011): 10-30.

2. Cookson, William. The alliance of genes and environment in asthma and allergy. Nature 402 (1999): 5-11.

3. Palmer CN, Irvine AD, Terron-Kwiatkowski A, Zhao Y, Liao H, Lee SP, et al. Common loss-of-function variants of the epidermal barrier protein filaggrin are a major predisposing factor for atopic dermatitis. Nat Genet 2006;38:441-6.

4. Gilliland, Frank D., et al. Effect of glutathione-S-transferase M1 and P1 genotypes on xenobiotic enhancement of allergic responses: randomised, placebo-controlled crossover study. The Lancet 363.9403 (2004): 119-125.

5. Lau, M. Y. Z., et al. CD14 polymorphisms, microbial exposure and allergic diseases: a systematic review of gene–environment interactions. Allergy 69.11 (2014): 1440-1453.

Number of Allergy-related Genes : 1195

Number of Diseases : 576

Number of Biomarkers : 60